Monoclonal antibody (UCHL1) that recognises normal and neoplastic T cells in routinely fixed tissues.
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چکیده
منابع مشابه
Monoclonal antibody (UCHL1) that recognises normal and neoplastic T cells in routinely fixed tissues.
UCHL1 is a murine monoclonal antibody that recognises a 180-185 kD determinant on CD4 (72%) and CD8 (36%) positive T cells. This antibody is effective in formalin fixed and paraffin embedded tissues, using the immunoperoxidase method. One hundred and forty three cases of malignant lymphoma were examined. Neoplastic cells in 100% of cases of Mycosis fungoides (n = 10), 83% of cases of peripheral...
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Formalin fixed and paraffin wax embedded tissue from 85 well characterised cases of non-Hodgkin's lymphoma and Hodgkin's disease were studied using the avidin-biotin-peroxidase complex technique. Among the non-Hodgkin's lymphomas all cases of B cell lymphoma were reactive with L26, a monoclonal antibody which is as yet an unclustered pan B cell reagent, with the exception of pre-B cell acute ly...
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AIMS To develop a monoclonal antibody specific for human macrophages in routinely processed material. METHODS The monoclonal antibody was derived from a mouse popliteal lymph node after subcutaneous immunisation in the footpad with fragments of human spleen depleted of lymphocytes and erythrocytes. RESULTS 3A5 is a monoclonal antibody reactive with macrophages, monocytes, and histiocytes in...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1986
ISSN: 0021-9746
DOI: 10.1136/jcp.39.4.399